Auranofin (Ridaura)
Generic available: no
Capsule size: 3 mg
Usual dose: one pill twice daily
Effective within: six weeks to six months
The introduction of auranofin in the 1980s allowed people with RA to take gold by mouth. This method of treatment can be effective in slowing the progression of RA, particularly if begun in the early stages of disease. Unlike injectable gold, oral gold is only 29 percent gold by weight. Many physicians believe that auranofin is not as effective as injectable gold.
Side effects of oral gold. Unlike injectable gold, auranofin therapy results in fewer serious side effects. The most common side effects are stomach cramping, diarrhea, nausea, and changes in appetite. Most of these problems can be made tolerable by starting with a low dose, taking the medication with meals, and consuming products containing bulk and large amounts of fiber such as Metamucil and Fiberall.
Before starting auranofin therapy discuss the following with your physician:
•      Previous history of blood disorders, kidney or liver disease, uncontrolled high blood pressure, bleeding problems, or allergic drug reactions.
While receiving auranofin:
•     Contact your physician promptly if you notice a rash or itching, mouth sores, increased bruising, an increased tendency to bleed, fever, cough, shortness of breath, or a change in skin or urine color.
•      Avoid unprotected or prolonged exposure to the sun.
•      Complete blood counts and urine studies need to be done frequently during therapy.
Pregnancy and breastfeeding. Discontinue gold therapy during pregnancy. Gold is excreted in breast milk, and the potential exists for serious adverse effects in the nursing infant. Mothers should discontinue either nursing or auranofin therapy.
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ARTHRITIS